Synthesis and antiinflammatory activity of derivatives of 2-aminothiophene-5-acetic acids

…, RD Syubaev, VI Shvedov, LM Alekseeva…

Index: Fedorova, I. N.; Syubaev, R. D.; Shvedov, V. I.; Alekseeva, L. M>; Shvarts, G. Ya.; Mashkovskii, M. D. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 1 p. 23 - 29 Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 1 p. 39 - 45

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Citation Number: 9

Abstract

Thiophene is an isoelectric analog (isostere) of benzene~ and in some cases the replacement of a benzene ring by a thiophene ring does not cause a significant decrease in biological activity. Thus, thi0phenealkane acids [ii] and aminothiophene derivatives have ...