Chemistry Letters

Application of High Pressure Induced by Water-freezing to the Michael Reaction of Alcohols with. ALPHA.,. BETA.-Enones.

Y Hayashi, K Nishimura

Index: Hayashi, Yujiro; Nishimura, Koichi Chemistry Letters, 2002 , # 3 p. 296 - 297

Full Text: HTML

Citation Number: 21

Abstract

High pressure (about 200 MPa), which was realized by freezing water in a sealed autoclave, has been successfully applied to a high-yield Michael reaction of alcohols and α, β- unsaturated ketones in the presence of a catalytic amount of DMAP and LiClO 4. Only a moderate yield was obtained under atmospheric pressure.