e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Aliphatic azoxy compounds. IV. Reaction of nitrosoalkanes with hydroxylamines. Synthesis of unsymmetrical primary and secondary azoxyalkanes by nitrogen- …
KG Taylor, SR Isaac, MS Clark Jr
Index: Taylor,K.G. et al. Journal of Organic Chemistry, 1976 , vol. 41, p. 1135 - 1140
The condensation of N-alkylhydroxylamines with photolytically monomerized nitrosoalkanes yields mixtures of 0-position isomers of 2 azoxyalkanes 5a-g and 6c-g in-30-95% yields. The major isomer is that one with the less bulky N substituent syn to the oxygen atom of the azoxy group. This isomer predominates regardless of whether the less bulky group is on the hydroxylamine or nitrosoalkane reactant. Use of N-alkyl-O-methylhydroxylamines in the ...