Accounts of chemical research

Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action

D Manna, G Roy, G Mugesh

Index: Das, Debasis; Roy, Gouriprasanna; Mugesh, Govindasamy Journal of Medicinal Chemistry, 2008 , vol. 51, # 22 p. 7313 - 7317

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Citation Number: 34

Abstract

Thyroid hormones are essential for the development and differentiation of all cells of the human body. They regulate protein, fat, and carbohydrate metabolism. In this Account, we discuss the synthesis, structure, and mechanism of action of thyroid hormones and their