Synthesis of monoesters as surfactants and drugs from D-glucose

…, P Gogalis, R Bikanga, P Godé, D Postel…

Index: Goueth, Pierre Y.; Gogalis, Pascalis; Bikanga, Raphael; Gode, Paul; Postel, Denis; et al. Journal of Carbohydrate Chemistry, 1994 , vol. 13, # 2 p. 249 - 272

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Citation Number: 26

Abstract

Abstract We have synthesized a series of monoesters from D-glucose corresponding to the structures 3-O-acyl, 6-O-acyl-1, 2-O-isopropylidene-α-D-glucofuranose and 3-O-acyl-D- glucose, following the sequence of reactions: D-glucose→ diacetone glucose→ acylation→ partial or total deprotection. These compounds were prepared as either potential non-ionic surfactants (fatty acid esters and perfluoroalkylated ester) or antitumour drugs (n-butyric ...