Tetrahedron Letters

Indium-mediated deoxygenation of amine-N-oxides in aqueous media

JS Yadav, BVS Reddy, MM Reddy

Index: Yadav; Subba Reddy; Reddy, M. Muralidhar Tetrahedron Letters, 2000 , vol. 41, # 15 p. 2663 - 2665

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Citation Number: 57

Abstract

Several aromatic and aliphatic amine-N-oxides were deoxygenated to the corresponding amines in good to quantitative yield using indium metal in neutral aqueous media. Other functional groups such as alkenes, halides, esters, ethers, nitriles, amides and sulfones are unaffected under the present reaction conditions.

~94%

~95%

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