Interaction of Alkyl 5, 6-Dialkyl-2-amino-3-cyano-4-pyridinecarboxylates with O-Nucleophiles. Synthesis of 6, 7-Dialkyl-4-amino-2, 3-dihydro-1H-pyrrolo [3, 4-c] …

…, AN Lyshchikov, OE Nasakin, OV Kayukova

Index: Vasiliev; Kayukov; Lyshchikov; Nasakin; Kayukova Chemistry of Heterocyclic Compounds, 2003 , vol. 39, # 9 p. 1182 - 1187

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Citation Number: 6

Abstract

The reaction of alkyl 5,6-dialkyl-2-amino-3-cyano-4-pyridinecarboxylates with certain O-nucleophiles was investigated, as a result of which 6,7-dialkyl-4-amino-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine -1,3- diones were synthesized. ... Keywords: amide, aminopyridines, enamines, isonicotinic acid, imide, nitriles, nucleophiles, pyridines, hydrolysis. ... Previously we reported the preparation of alkyl 5,6-dialkyl-2-amino-3-cyano-4-pyridinecarboxylates 1a-d [1]. The presence in ...