Biologically active substances in hydrazide derivatives of succinic heterylamides

VP Chernykh, VI Kabachnyi, VA Shapovalova…

Index: Chernykh, V. P.; Kabachnyi, V. I.; Shapovalova, V. A.; Porokhnyak, L. A.; Beletskaya, O. V.; Savchenko, V. N. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 7 p. 575 - 578 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 7 p. 825 - 828

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Abstract

The starting hydrazides (Ia-c) were obtained by methods [4, 6]. Acylation of the hydrazides by carboxylic anhydrides and chloroanhydrides in~ dioxane as well as by arensuifochlorides in a pyridine medium was accompanied by the formation of the corresponding acyl-and arensulfohydrazides~(IIa-g and IIIa-g, respectiv~ ly). The ilidene, hydrazides (IVa-d), obtained by reacting the hydrazides I and aldehydes in boiling DMFA, ...