Tetrahedron letters

Efficient access to 3-alkyl-trifluoromethylbenzenes using Kumada's coupling reaction

N Roques, L Saint-Jalmes

Index: Roques, Nicolas; Saint-Jalmes, Laurent Tetrahedron Letters, 2006 , vol. 47, # 20 p. 3375 - 3378

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Citation Number: 10

Abstract

Trifluoromethyl aromatic derivatives form the most important family of fluorinated intermediates used in agrochemical, pharmaceutical and performances markets 1 such as liquids crystals. Pharmaceutical and agrochemical companies are more and more interested in trifluoromethylbenzene derivatives bearing a carbon functionalized function in addition to the CF 3 moiety, such as 3-methyl-trifluoromethylbenzene, 3-trifluoromethylbenzylalcohol and 3- ...