Abstract: Silver (1) activation of pyridyl thioglycosides in the presence of carbon nucleophiles yield C-glycosides under mild conditions with high stereoselectivity. Pyridyl thioglycosides of suitably protected carbohydrates represent stable precursors to structurally complex C-glycosides. Per-O-benzyl-(2'-thiopyridyl)-~-glucose (l), per-O-benzy1-(2'- thiopyridyl)-o-ribose (2), and 1-(2'-thiopyridyl)-2, 3-Oisopropylidene-5-O-(te~~- ...
