Total synthesis of bernumicine and bernumidine, two alkaloids from Berberis nummularia

…, PY Chavant, MT Averbuch-Pouchot…

Index: Pinet; Chavant; Averbuch-Pouchot; Vallee Journal of Chemical Research - Part S, 2001 , # 2 p. 65 - 67

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Abstract

Plants of the genus Berberis have been used in traditional medicine for centuries in various part of the world. This is the case for the common barberry (Berberis vulgaris) whose bark is known to give a tonic, purgative and antiseptic extract. The chief constituent of barberry barks is berberine (1) (Scheme 1).1 This compound has many interesting biological proper- ties, including activity against bacteria, fungi and viruses. Berberine is also present in the roots of B. aquifolium ...