Integration of chemical and biological catalysis: production of furylglycolic acid from glucose via cortalcerone

…, E Taarning, MD Mozuch, J Gaskell, D Cullen…

Index: Schwartz, Thomas J.; Goodman, Samuel M.; Osmundsen, Christian M.; Taarning, Esben; Mozuch, Michael D.; Gaskell, Jill; Cullen, Daniel; Kersten, Philip J.; Dumesic, James A. ACS Catalysis, 2013 , vol. 3, # 12 p. 2689 - 2693

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Citation Number: 17

Abstract

Furylglycolic acid (FA), a pseudoaromatic hydroxy-acid suitable for copolymerization with lactic acid, can be produced from glucose via enzymatically derived cortalcerone using a combination of Brønsted and Lewis acid catalysts. Cortalcerone is first converted to furylglyoxal hydrate (FH) over a Brønsted acid site (HCl or Al-containing beta-zeolite), and FH is subsequently converted to FA over a Lewis acid site (Sn-beta zeolite). Selectivity for ...