Tetrahedron letters

Reductive heterocyclizations via indium/iodine-promoted one-pot conversion of 2-nitroaryl aldehydes, ketones, and imines

R Han, KI Son, GH Ahn, YM Jun, BM Lee, Y Park…

Index: Han, Rongbi; Son, Kee In; Ahn, Gil Hwan; Jun, Young Moo; Lee, Byung Min; Park, Younbong; Kim, Byeong Hyo Tetrahedron Letters, 2006 , vol. 47, # 41 p. 7295 - 7299

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Citation Number: 20

Abstract

2-Nitroaryl aldehydes, ketones, and imines were reductively cyclized to 2, 1-benzisoxazoles with good yields in the presence of indium and iodine in MeOH. Under a similar condition, N- (2-nitrobenzylidene) anilines were produced mixtures of 2, 1-benzisoxazoles and 3-anilino- 2-phenyl-2H-indazoles.