Converting One-Face α-Helix Mimetics into Amphiphilic α-Helix Mimetics as Potent Inhibitors of Protein–Protein Interactions

JH Lee, M Oh, HS Kim, H Lee, W Im…

Index: Jung, Kwan-Young; Vanommeslaeghe, Kenno; Lanning, Maryanna E.; Yap, Jeremy L.; Gordon, Caryn; Wilder, Paul T.; Mackerell, Alexander D.; Fletcher, Steven Organic Letters, 2013 , vol. 15, # 13 p. 3234 - 3237

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Abstract

... Sci. , Article ASAP. DOI: 10.1021/acscombsci.5b00080. Publication Date (Web): December 11, 2015. Copyright © 2015 American Chemical Society. *E mail: hslim@postech.ac.kr. ... Table 1. Synthesized Amphiphilic α-Helix Mimetics 1a–t for Evaluation as Mcl-1 Inhibitors. ...