e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Antitumor agents among indole sulfonamide derivatives

AA Chachoyan, VA Shkulev, KG Samvelyan…

Index: Chachoyan, A. A.; Shkulev, V. A.; Samvelyan, K. G.; Garibdzhanyan, B. T.; Papayan, G. L. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 2 p. 126 - 129 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 2 p. 166 - 169

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Citation Number: 1

Abstract

We proved the position of the introduced sulfoxychloride group by comparing the PMR- spectra of the synthesized acids IVa-g to the PMR-spectrum of ethyl 5-sulfo-2- ethoxycarbonylindole-3-carboxylate obtained by the Fischer reaction and methods [3], as well as by establishing the PMR-spectra and mp of compound VI and 5- dimethylaminosulfonamide indole which was synthesized by the indolin-indole method as ...

N,N-diethyl-3-formyl-1H-indole-5-sulfonamide Structure

N,N-diethyl-3-f...

~51%

5-(diethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(diethylsulfa...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

5-(diethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(diethylsulfa...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

5-(diethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(diethylsulfa...

5-(morpholinosulfonyl)-1H-indole-3-carbaldehyde Structure

5-(morpholinosu...

~49%

5-morpholin-4-ylsulfonyl-1H-indole-3-carboxylic acid Structure

5-morpholin-4-y...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

5-morpholin-4-ylsulfonyl-1H-indole-3-carboxylic acid Structure

5-morpholin-4-y...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

5-morpholin-4-ylsulfonyl-1H-indole-3-carboxylic acid Structure

5-morpholin-4-y...

N,N-bis(2-chloroethyl)-3-formyl-1H-indole-5-sulfonamide Structure

N,N-bis(2-chlor...

~48%

5-[bis(2-chloroethyl)sulfamoyl]-1H-indole-3-carboxylic acid Structure

5-[bis(2-chloro...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

5-[bis(2-chloroethyl)sulfamoyl]-1H-indole-3-carboxylic acid Structure

5-[bis(2-chloro...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

5-[bis(2-chloroethyl)sulfamoyl]-1H-indole-3-carboxylic acid Structure

5-[bis(2-chloro...

3-formyl-N,N-dimethyl-1H-indole-5-sulfonamide Structure

3-formyl-N,N-di...

~48%

5-(dimethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(dimethylsulf...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

5-(dimethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(dimethylsulf...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

5-(dimethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(dimethylsulf...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

N,N-dimethyl-1H-indole-5-sulfonamide Structure

N,N-dimethyl-1H...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

N,N-dimethyl-1H-indole-5-sulfonamide Structure

N,N-dimethyl-1H...

3-formyl-N,N-dimethyl-1H-indole-5-sulfonamide Structure

3-formyl-N,N-di...

~%

N,N-dimethyl-1H-indole-5-sulfonamide Structure

N,N-dimethyl-1H...

5-(dimethylsulfamoyl)-1H-indole-3-carboxylic acid Structure

5-(dimethylsulf...

~31%

N,N-dimethyl-1H-indole-5-sulfonamide Structure

N,N-dimethyl-1H...

3-formyl-N,N,1-trimethyl-1H-indole-5-sulfonamide Structure

3-formyl-N,N,1-...

~51%

5-(dimethylsulfamoyl)-1-methylindole-3-carboxylic acid Structure

5-(dimethylsulf...

Indole-3-carboxaldehyde Structure

Indole-3-carbox...

~%

5-(dimethylsulfamoyl)-1-methylindole-3-carboxylic acid Structure

5-(dimethylsulf...

5-chlorosulfonyl-3-formylindole Structure

5-chlorosulfony...

~%

5-(dimethylsulfamoyl)-1-methylindole-3-carboxylic acid Structure

5-(dimethylsulf...

3-formyl-N,N-dimethyl-1H-indole-5-sulfonamide Structure

3-formyl-N,N-di...

~%

5-(dimethylsulfamoyl)-1-methylindole-3-carboxylic acid Structure

5-(dimethylsulf...