Use of a. DELTA. 1-Piperidine for the Synthesis of a Differentially Protected Diamine Intermediate for the Preparation of the Iron Siderophore Desferrioxamine

PGM Wuts, JE Cabaj, JL Havens

Index: Wuts, Peter G. M.; Cabaj, John E.; Havens, Jeff L. Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6470 - 6471

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Citation Number: 5

Abstract

OH desferrioxamine (7) than concentrating it. Since chloroamines are known to be thermally unstable, no effort was made to isolate and characterize the intermediate. The onset temperature for the decomposition of the chloroamine I MTBE solution is 110" C as determined by differential scanning calorimetry and the neat liquid decomposes rapidly and exothermically at 65" C. These results show that the original procedure of ref 7 is not very ...