α-Isopropyl-α-[3-[3-(3-methoxyphenoxy) propylamino] propyl]-α-phenylacetonitrile derivatives containing various substituents on the benzene ring (A ring) at the phenylacetonitrile moiety were prepared, and their Ca 2+-antagonistic activity was evaluated. Among these compounds, the N-Me derivatives with m-OMe, pF, p-Cl, 3, 4-(OMe) 2 and 3, 5-(OMe) 2 substituents on the A ring were found to show higher Ca 2+- ...
