To construct a smart artificial antioxidative enzyme on a nano-scaffold, a novel method for designing glutathione peroxidase (GPx) active sites on block copolymer vesicles was developed by simple blending predesigned temperature-sensitive block copolymers with the main catalytic units of GPx. A series of functional block copolymers, poly (N- isopropylacrylamide)-b-polyacrylamides loaded with recognition and catalytic sites, were ...