Synthesis of [D5??ethyl]??tamoxifen; a mechanistic probe of tamoxifen induced hepatic DNA adduct formation

MN Horton, M Jarman, GA Potter

Index: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 34, # 8 p. 767 - 772

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Abstract

Page 1. Journal of Labelled Cornpounds and Radiopltal.maceuficals-Vo1. XXXIV, No. 8 ... compound 2 as white crystals (0.904 g, 89 %), nip 98-100 'C. IR (KBr disc) u/cm-' 2224 (CD), 1610 (C=C). 'H-NMR (CDCl,) 6 2.29 (6H, s, N&), 2.65 (2H, t, J 5.8 Hz, OCH2C&NMez), ...