e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Organic letters

First asymmetric synthesis of trans-3, 4-dimethyl-4-arylpiperidines

DP Furkert, SM Husbands

Index: Organic Letters, , vol. 9, # 19 p. 3769 - 3771

Full Text: HTML

Citation Number: 9

Abstract

... Volume: Page: ... Organic Letters. ... We were pleased to find that NMR analysis of 17 with the chiral complexing agent (S)-(+)1-(9-anthryl)-2,2,2-trifluoroethanol 4a,14 indicated the presence of only one enantiomer to the limits of NMR detection. ...

(S)-4-bromo-1-(tert-butylsulfonyl)-1,2,3,6-tetrahydropyridin-3-ol Structure

(S)-4-bromo-1-(...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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(S)-4-bromo-1-(tert-butylsulfonyl)-1,2,3,6-tetrahydropyridin-3-yl diethyl phosphate Structure

(S)-4-bromo-1-(...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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N/A Structure

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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N/A Structure

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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4-bromo-1-(tert-butylsulfonyl)-1,6-dihydropyridin-3(2H)-one Structure

4-bromo-1-(tert...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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4-Boronoanisole Structure

4-Boronoanisole

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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(+)-1,3(R),4(R)-Trimethyl-4-(3-methoxyphenyl)piperidine Structure

(+)-1,3(R),4(R)...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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N/A Structure

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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(R)-4-(3-methoxyphenyl)-3-methyl-1,2,3,6-tetrahydropyridine Structure

(R)-4-(3-methox...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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(R)-4-(3-methoxyphenyl)-1,3-dimethyl-1,2,3,6-tetrahydropyridine Structure

(R)-4-(3-methox...

~%

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE Structure

(+)-(3R,4R)-3,4...

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Methylboronic acid Structure

Methylboronic acid

(R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine Structure

(R)-(+)-2-(Diph...

~%

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Structure

(R)-3,3-Dipheny...

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Synthesis and absolute configuration of LY255582, a potent o...

[Journal of Organic Chemistry, , vol. 56, # 4 p. 1660 - 1663]

Synthesis of trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperid...

[Journal of Organic Chemistry, , vol. 61, # 2 p. 587 - 597]

Synthesis of trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperid...

[Journal of Organic Chemistry, , vol. 61, # 2 p. 587 - 597]