Addition Reactions of Chloro-or Iodomethyllithium to Imines. Synthesis of Enantiopure Aziridines and β-Chloroamines

JM Concellón, H Rodríguez-Solla…

Index: Barluenga, Jose; Fernandez-Simon, Jose L.; Concellon, Jose M.; Yus, Miguel Synthesis, 1987 , # 6 p. 584 - 586

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Citation Number: 33

Abstract

We report a novel, simple, and efficient synthesis of aziridines and 1-chloroalkan-2-amines by the reaction of imines derived from various aldehydes and p-toluenesulfonamide or benzenesulfonamide with iodo-or chloromethyllithium, respectively. Both halogenated

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