Iron/Amino Acid Catalyzed Direct N??Alkylation of Amines with Alcohols

Y Zhao, SW Foo, S Saito

Index: Zhao, Yingsheng; Foo, Siong Wan; Saito, Susumu Angewandte Chemie - International Edition, 2011 , vol. 50, # 13 p. 3006 - 3009

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Citation Number: 94

Abstract

Higher amines are widely used in both the bulk and fine chemical industries as fundamental materials, additives, dyes, agrochemicals, etc.[1] Therefore, the development of a selective N- alkylation method that is cost effective, salt free, and environmentally benign is of considerable interest. However, the most common strategies to produce secondary or tertiary amines involve treating a primary amine with an alkylating reagent having a good ...