Prostaglandin D 2 (PGD 2 ) is derived from the metabolism of arachidonic acid by cyclooxygenases and downstream PGD 2 synthases. In the immune system, PGD 2 is mainly produced by mast cells 1 but also although at lower levels, by macrophages and Th2 lymphocytes. 2 PGD 2 binds to three different receptors, the thromboxane type prostanoid receptor (TP), 3 the PGD 2 receptor (DP, also known as DP1) 4 and the chemoattractant receptor homologous molecule ...
[Attaryan, O. S.; Sahakyan, A. A.; Akopyan, A. E.; Sahakyan, L. A.; Asratyan, G. V. Russian Journal of General Chemistry, 2012 , vol. 82, # 9 p. 1610 - 1612,3 Zhurnal Obshchei Khimii, 2012 , vol. 82, # 9 p. 1575 - 1577]
[Attaryan, O. S.; Sahakyan, A. A.; Akopyan, A. E.; Sahakyan, L. A.; Asratyan, G. V. Russian Journal of General Chemistry, 2012 , vol. 82, # 9 p. 1610 - 1612,3 Zhurnal Obshchei Khimii, 2012 , vol. 82, # 9 p. 1575 - 1577]