Canadian Journal of Chemistry

Total synthesis of δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine (ACV), a biosynthetic precursor of penicillins and cephalosporins

S Wolfe, MG Jokinen

Index: Pellicciari, Roberto; Natalini, Benedetto; Marinozzi, Maura Synthetic Communications, 1988 , vol. 18, # 14 p. 1707 - 1714

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Citation Number: 43

Abstract

... Conversion to fully protected ACV (9; see Scheme 1) was achieved using EEDQ (18) as the coupling agent. ... Page 3. CAN. I. CHEM. VOL. 57, 1979 OH OH 0H.(C6H, ,),NH ... The solution was concentrated to half its original volume and an orange precipitate was removed. ...