ABSTRACT Six spectrophotometric methods for determination of eszopiclone have been developed, validated and applied for the assay of the drug in pharmaceuticals. Methods A, B, C and D are based on ion pair complexation of drug, in acidic buffers, with triphenylmethane dyes viz., Bromothymol blue (BTB), Bromophenol blue (BPB), Bromocresol green (BCG) and Bromocresol purple (BCP). The complexes are extracted ...