Tetrahedron letters

Facile generation of aziridines from the reaction of α-diazoamides with tethered oximino-ethers

MC McMills, DL Wright, JD Zubkowski, EJ Valente

Index: McMills, Mark C.; Wright, Dennis L.; Zubkowski, Jeffrey D.; Valente, Edward J. Tetrahedron Letters, 1996 , vol. 37, # 40 p. 7205 - 7208

Full Text: HTML

Citation Number: 20

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... In an attempt to prepare azomethine ylide intermediates for cycloaddition reactions with electron deficient olefins, oximino-ethers with tethered α-diazoamide moieties were reacted in the presence of metal catalyst. The reaction resulted in aziridine formation preferentially.

~10%

~96%

Intramolecular aziridination: Decomposition of diazoamides w...

[Wright, Dennis L.; McMills, Mark C. Organic Letters, 1999 , vol. 1, # 4 p. 667 - 670]

A versatile synthesis of 2-substituted 4-amino-1, 2, 4, 5-te...

[Van Rompaey, Karolien; Van Den Eynde, Isabelle; De Kimpe, Norbert; Tourwe, Dirk Tetrahedron, 2003 , vol. 59, # 24 p. 4421 - 4432]

A versatile synthesis of 2-substituted 4-amino-1, 2, 4, 5-te...

[Tetrahedron, , vol. 59, # 24 p. 4421 - 4432]

Synthesis and structure–activity relationships of potential ...

[Ho, Bin; Michael Crider; Stables, James P European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 265 - 286]

A versatile synthesis of 2-substituted 4-amino-1, 2, 4, 5-te...

[Tetrahedron, , vol. 59, # 24 p. 4421 - 4432]