The metabolism of ethylene dibromide (EDB)has been studied after administration of this compound to rats by stomach tube. N-acetyl-S-Cl1- nydroxyethyljcysteine was isolated from the urine of EDB-dosed rats. The identity of this compound with synthetic N-acetyl-S-(~-hydroxyethyl)cysteine was proved by chromatographic and electrophoretic methods and by identification of the products obtained by acid and alkaline hydrolysis, by enzymatic hydrolysis and oxidation to a ...
