Acyl and sulfonyl isocyanates in. beta.-lactam synthesis

AGM Barrett, MJ Betts, A Fenwick

Index: Barrett, Anthony G. M.; Betts, Michael J.; Fenwick, Ashley Journal of Organic Chemistry, 1985 , vol. 50, # 2 p. 169 - 175

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Citation Number: 38

Abstract

The/3-lactam ring system occurs widely in several structurally diverse classes of clinically important antibacterial agents. These include the penicillins, the cephalosporins, the nocardicins, the carbapenems, and the monobactams.'Since these antibiotics are widely applied in human medicine, a plethora of structural variations has been prepared by partial and total synthesis. These