Lewis Acid Mediated Nucleophilic Ring-Opening of 1-Benzhydryl Azetidine-3-ol with Aryl Alcohols: A Formal Synthesis of Carvedilol

…, H Ramamohan, A Ganesh, K Srinivas…

Index: Krishna Reddy; Ramamohan; Ganesh; Srinivas; Mukkanti; Madhusudhan Asian Journal of Chemistry, 2012 , vol. 24, # 8 p. 3468 - 3472

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Abstract

FT-IR spectra were recorded as KBr pellet on Nicolet 380 FT-IR Instrument (Model Thermo Electron Corporation-Spectrum One), 1H and 13C NMR (proton decoupled) spectra were recorded on Varian 400 MHz spectrometer using DMSO-d6 and CDCl3 as solvent and tetramethylsilane (TMS) as internal standard. Mass spectra were recorded on Agilent triple quadrupole mass spectrometer equipped with turboion spray interface at 375 C. All the organic extracts were dried over ...