Some cardiovascular effects of a series of aryloxyalkylamines. I

J Augstein, WC Austin, RJ Boscott…

Index: Augstein,J. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 356 - 367

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Citation Number: 61

Abstract

Pharmacology.-The pharmacological effects on adrenergic neuroeff ector transmission of the compounds described were studied in cats and dogs anesthetized with chloralose. All active compounds antagonized both the contractions of the cat nictitating membrane in response to pre-and postganglionic stimulation of the cervical sympathetic trunk and those to injected epinephrine and norepinephrine. The pressor effects of injected ...