e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Singlet oxygen in synthesis. Formation of d, l-and meso-isochrysohermidin from a 3, 3′-bipyrrole precursor
…, R Frechette, RW DeSimone, JU Yoo, CM Baldino
Index: Wasserman, Harry H.; Rotello, Vincent M.; Frechette, Roger; DeSimone, Robert W.; Yoo, Ji Uk; Baldino, Carmen M. Tetrahedron, 1997 , vol. 53, # 26 p. 8731 - 8738
A synthesis of the d, l and meso forms of isochrysohermidin 3 is outlined which employs the singlet oxygen oxidation of pyrroles as the key step. The bipyrrole precursor 8 was synthesized from a 3-hydroxy monopyrrole which, in turn, was prepared by addition of methylamine to a vinyl vicinal tricarbonyl.
