Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa

…, K Ninomiya, K Imura, H Matsuda, M Yoshikawa…

Index: Morikawa, Toshio; Pan, Yingni; Ninomiya, Kiyofumi; Imura, Katsuya; Matsuda, Hisashi; Yoshikawa, Masayuki; Yuan, Dan; Muraoka, Osamu Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 5 p. 1882 - 1890

Full Text: HTML

Citation Number: 48

Abstract

The methanolic extract from fresh stems of Cistanche tubulosa (Orobanchaceae) was found to show hepatoprotective effects against d-galactosamine (d-GalN)/lipopolysaccharide (LPS)-induced liver injury in mice. From the extract, three new phenylethanoid oligoglycosides, kankanosides H1 (1), H2 (2), and I (3), were isolated together with 16 phenylethanoid glycosides (4–19) and two acylated oligosugars (20, 21). The structures of ...