In situ evaluation of kinetic resolution catalysts for nitroaldol by rationally designed fluorescence probe

…, Y Takahashi, Y Mori, T Terai, T Nagano

Index: Gabe, Yu; Urano, Yasuteru; Kikuchi, Kazuya; Kojima, Hirotatsu; Nagano, Tetsuo Journal of the American Chemical Society, 2004 , vol. 126, # 10 p. 3357 - 3367

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Citation Number: 11

Abstract

Development of effective chemical catalysts is a key concern in organic chemistry. Therefore, convenient screening systems for chemical catalysts are required, and although some fluorescence-based HTS systems have been developed, little attempt has been made to apply them to asymmetric catalysts. Therefore, we tried to develop a chiral fluorescence probe which can evaluate the reactivity and enantioselectivity of asymmetric catalysts. We ...