Antihypertensive 9-substituted 1-0xa-4, 9-diazaspiro [5.5] undecan-3-ones

…, JM Caroon, DB Repke, AM Strosberg…

Index: Clark; Caroon; Repke; Strosberg; Bitter; Okada; Michel; Whiting Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 855 - 861

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Citation Number: 10

Abstract

The compounds in Table I were tested for antihypertensive activity in male, Okamoto-Aoki strain, spontaneously hypertensive rats (SHR). The data in Table I represent the percentage decrease in systolic blood pressure for the drug-treated group relative to the value for the untreated control.