An efficient synthesis of tetrahydroindoles with different substituents in position 1 is described. Microwave-assisted aminolysis of 4-oxo-4, 5, 6, 7-tetrahydrobenzofuran with different primary amines gives the corresponding tetrahydroindoles in few minutes. All attempts to use microwave dielectric heating to reduce the time required for preparation of 4- oxo-4, 5, 6, 7-tetrahydrobenzofuran, starting from 1, 3-cyclohexandione were on the other ...
