Imidazo [1, 2-a] pyridines: orally active positive allosteric modulators of the metabotropic glutamate 2 receptor

AA Trabanco, G Tresadern, GJ Macdonald…

Index: Journal of Medicinal Chemistry, , vol. 55, # 6 p. 2688 - 2701

Full Text: HTML

Citation Number: 35

Abstract

... Journal of Medicinal Chemistry. ... Neuroscience Medicinal Chemistry, ∥ Neuroscience Biology ... Over recent years, the number of reported mGlu2 receptor PAM chemical series has increased significantly (Figure 2).(15). figure Figure 2. Known mGlu2 potentiator chemotypes. ...