Based on the N-(phenethyl) azole backbone of azole antifungals, we designed 1-[(2- benzyloxy) phenyl]-2-(azol-1-yl) ethanone derivatives 2 and 3, containing benzyloxyphenyl scaffold of croconazole. Also these compounds can be considered as flexible analogs, resulted from C2–C3 disconnection of 3¢-chloro-3-imidazolylflavanone 1, recently described as antifungal agent. Thus, in this report, we describe the synthesis of 1-[(2-benzyloxy) ...
