Chemical Communications

A mild and efficient method for the deprotection of tert-butyldimethylsilyl ethers using iodine in methanol

AR Vaino, WA Szarek

Index: Vaino, Andrew R.; Szarek, Walter A. Chemical Communications, 1996 , # 20 p. 2351 - 2352

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Citation Number: 50

Abstract

A mild and efficient method for the deprotection of tert-butyldimethylsilyl ethers using iodine in methanol ... Andrew R. Vaino and Walter A. Szarek*? Department of Chemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada ... An effective method for the cleavage of tert-butyldimethyl- silyl ethers using a 1% solution of iodine in methanol is described. ... The protection and deprotection of the hydroxy functional group remain critical challenges to ...