A Straightforward Organocatalytic Alkylation of 2??Arylacetaldehydes: An Approach towards Bisabolanes

A Gualandi, P Canestrari, E Emer…

Index: Gualandi, Andrea; Canestrari, Pietro; Emer, Enrico; Cozzi, Pier Giorgio Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 528 - 536

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Citation Number: 10

Abstract

Abstract: A highly stereoselective organocatalytic aalkylation of 2-arylacetaldehydes with a commercially available carbenium tetrafluoroborate is described. The stereoselective alkylation was carried out in acetonitrile/water, under air in the presence of a commercially available imidazolidinone (MacMillan s catalyst). Key intermediates for the synthesis of bisabolanes were obtained through a simple chemistry. In particular a direct, ...