Silyl modification of biologically active compounds. 3. organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline, tetrahydroisoquinoline, and …

…, I Segal, A Zablotskaya, S Germane

Index: Lukevits; Segal; Zablotskaya; Germane Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 6 p. 682 - 688

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Citation Number: 5

Abstract

Abstract The N-(2′-hydroxyethyl)-1, 2, 3, 4-tetrahydroquinoline,-isoquinoline, and- silaisoquinoline, and their trimethyland triethylsilyl derivatives and the corresponding methiodides were synthesized. The acute toxicity and psychotropic activity of the compounds synthesized were studied.

~38%

~25%

The synthesis of some alcohols derived from 1, 2, 3, 4-tetra...

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Silyl modification of biologically active compounds. 13. Syn...

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