Tetrahedron

Synthesis of N-protected indolaldehydes using modified Hass procedure

R Balamurugan, AK Mohanakrishnan

Index: Balamurugan, Ramalingam; Mohanakrishnan, Arasambattu K. Tetrahedron, 2007 , vol. 63, # 45 p. 11078 - 11085

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Citation Number: 9

Abstract

Oxidation of benzylic bromide into the corresponding aldehydes is one of the most significant transformations in organic synthesis. Plenty of methods have been developed for the conversion of benzyl halides into their corresponding carbonyl compounds. Most commonly used reagents for conversion of benzylic bromides into the corresponding aldehydes are hexamethylene tetramine, 1 dimethyl sulfoxide, 2 (Bu 4 N) 2 Cr 2 O 7 , 3 pyridine-N-oxide, 4 3,6-bis( ...