European journal of organic chemistry

Selective Palladium??Catalysed ipso Arylation of α, α??Disubstituted Benzo [b] thien??2??ylmethanols with Aryl Bromides using PCy3 as Ligand

AB Biro, A Kotschy

Index: Biro, A. Beatrix; Kotschy, Andras European Journal of Organic Chemistry, 2007 , # 8 p. 1364 - 1368

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Citation Number: 13

Abstract

Abstract α, α-Diphenylbenzo [b] thien-2-ylmethanol was treated with a series of aryl bromides in the presence of palladium (II) acetate and tricyclohexylphosphane to give the appropriate 2-aryl-benzo [b] thiophenes in good to excellent yield with concomitant formation of benzophenone. The reaction wassuccessfully extended to α, α-diphenylbenzo [b] thien-3-ylmethanol, although in certain cases the transformation was biased by ...