probably the hydration product of the minor 2-cis substrate. 2a might have come partly from the major 2-trans substrate by the action of a trans-cis isomerase, as was found in the metabolic course of epoxyfarnesol.* Metabolite 4b, oil,[a] D-6.6'(c 0.2, MeOH), was identified as methyl (1 1S)-truns, truns-lO-oxo-l I-hydroxyhomofarnesoate, which was clearly an oxidation product of 3a at Clo. Terminal oxidation of an allylic carboxylate in 3a gave an ...
