Synthesis of pyrroles under mild conditions using PCl 3, ketones, and alkylhydrazines

G Baccolini, C Sandali

Index: Baccolini, Graziano; Sandali, Claudio Journal of the Chemical Society, Chemical Communications, 1987 , p. 788 - 789

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Citation Number: 9

Abstract

Pyrroles represent an important major class of heterocycles1 and their prominent role in organic synthesis leads to continuing development of new methods of preparing pyrroles. Symmetrically substituted pyrroles are usually pre- pared through variations of the Piloty-Robinson synthesis using the respective ketoazine as intermediate.2 However, this reaction needs drastic conditions and often the yields are very poor.3 In the last few years we have found4 that reaction at