Direct guanidinylation of aryl and heteroaryl halides via copper-catalyzed cross-coupling reaction

…, F Bihel, C Antheaume, JJ Bourguignon

Index: Hammoud, Hassan; Schmitt, Martine; Bihel, Frederic; Antheaume, Cyril; Bourguignon, Jean-Jacques Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 417 - 423

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Citation Number: 20

Abstract

Over the past decade, the copper-catalyzed modified Ullmann reaction has emerged as a powerful approach by means of additive copper chelating agents.(9) Moreover, it could be extended to other nitrogen-containing reagents such as anilines, amides, and carbamates.(10) Progress has been obtained through the use of various copper-chelating agents (α-aminoacids, β-aminoacids, phenolic derivatives, or ethylenediamine derivatives), which dramatically ...