Tetrahedron

Synthesis, complexation study and reactivity of annelated thiophenic nadh models

…, T Trefouel, G Dupas, J Bourguignon, G Queguiner

Index: Cazin, J.; Trefouel, T.; Dupas, G.; Bouguignon, J.; Queguiner, G. Tetrahedron, 1988 , vol. 44, # 4 p. 1079 - 1090

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Citation Number: 12

Abstract

The synthesis of two carbonyl 4, 7-dihydrothieno (2, 3) pyridines 1a and 1b is described. These derivatives are potential new NADH models. A NHR study of the complexation of magnesium ions by these compounds has been performed. The behaviour of the thieno [2, 3- b) derivative is different of that of the thieno [3, 2-b] derivative: in the former the sulfur atom plays an important role in the complexation. The biomimetic reduction of p. ...