Abstract The synthesis and antidepressant properties of a new pyrimido [4, 5-d] pyrimidine are described. Spectral data determined in solution and in the solid state allowed establishment of the relationship between the activity and the conformation of the molecule. The spatial structure seems to be in accordance with a possible binding at the presynaptic α- receptor sites.
![Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione,5,6,7,8-tetrahydro-1,3-dimethyl-6-(phenylmethyl)- Structure](https://image.chemsrc.com/caspic/432/71803-56-0.png)