The synthesis of new spiro β-lactam and thiazolidinone compounds incorporating quinones and their biological activity

…, NAA El-Kanzi, HA Soleiman, M Younis

Index: Khalafallah; El-Kanzi; Soleiman; Younis Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 11 p. 2483 - 2503

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Citation Number: 8

Abstract

A series of some fused and spiro heterocyclic compounds such as pyrazolines, isoxazolines, pyrimidines, β-lactams, and thiazolidinone derivatives incorporating compounds 3, 6a–d, 7a– d, 9a–c, 10a–c, 11a–c, 12a–c, and 13a–c have been synthesized by a cycloaddition and cyclocondensation reaction of monochloroacetyl chloride, mercaptoacetic acid, hydrazines, hydroxylamine, urea, and thiourea with the prepared 5a–d and 8a–c.