Conclusion We can expect that other heterolytic decarboxylation reactions will show positive @ secondary kinetic isotope effects and that reactivity will be a major determinant of ... Acknowledgment. We thank the Natural Sciences and Engineering Research Council of Canada for support through an operating grant (RK) and a fellowship (MB). We thank Professor KT Leffek for helpful comments, Registry No. 1 t-Bu ester, 54441-66-6; 2t-Bu ester, 104015- 38-5; 4, ...
