Chemistry of Heterocyclic Compounds

Synthesis of 1-Aryl-4-azolylbutanones

DA Karachev, SV Popkov

Index: Karachev; Popkov Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 8 p. 987 - 993

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Abstract

Abstract A convenient method was developed for the synthesis of substituted 4-azolyl-1- arylbutanones from the available γ-chlorobutyrophenones by successive stages of transformation into ketals, alkylation of sodium imidazolate or 1, 2, 4-triazolate by the ketals